Case Report
Year: 2019 | Month: February | Volume: 6 | Issue: 2 | Pages: 196-198
A Case Report on Coumarin Derivatives Induced Coagulopathy
Kavya. L1, Sudharani. K1, Yerni Kumar2
1Pharm. D, 2M Pharmacy,
Department of Clinical Pharmacy, Star Hospital, Banjarahills, Hyderabad, Telangana, India.
Corresponding Author: Sudharani. K
ABSTRACT
Coumarins are effective for the prevention and treatment of venous and arterial thrombosis but may cause bleeding (especially if overdosed) or thrombosis (especially if under) To minimize the risk of these complications, the prothrombin time (PT) - generally expressed as the international normalized ratio (INR) is used to monitor the degree of coumarin-associated anticoagulation We describe a case of a 50-years male patient with atrial fibrillation with FVR who presented with complaints of abdominal pain at right hypochondrial region radiating to right shoulder since 10 days & also complaint of low grade fever, nausea, decreased appetite. Lab investigations showed increased PT and INR ratio based on that patient diagnosed as Acitrom induced Coagulopathy. Occurrence of Coagulopathy is a known complication of vitamin k antagonist. So providing counselling regarding all aspects of medications as well as lifestyle modifications and by giving patient information leaflets were most important for this condition
Key words: Acitrom, INR, PT, Coagulopathy.
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