Research Paper
Year: 2019 | Month: June | Volume: 6 | Issue: 6 | Pages: 85-93
>Chitosan Catalyzed One-Pot Three-Component Conventional Synthesis of 1,2-Dihydro-1-Arylnaphtho[1,2-e][1,3]Oxazine-3-Ones
K. Narasimha Reddy1,2, S. Ramanaiah1, N. Ananda Kumar Reddy1,3
1Department of Chemistry, Rayalaseema University, Kurnool - 518 007, India
2Department of Chemistry, Srihari Degree & PG College, Kadapa - 516 003, India
3Department of Chemistry, Sri Venkateswara Degree & PG College, Kadapa - 516 003, India
Corresponding Author: N. Ananda Kumar Reddy
ABSTRACT
A series of 1,2-dihydro-1-arylnaphtho[1,2-e] [1,3] oxazine-3-ones was synthesized from the reaction of various substituted aldehydes, β-naphthol and urea by using Chitosan, a naturally occurring ecofriendly polymer material as catalyst. The structures of all the title compounds were characterized by spectral (IR, 1H, 13C NMR & MASS spectra) and elemental (CHN) analysis. This heterogeneous catalysis had accomplished products with high yields in short reaction times in an eco-friendly approach and the catalyst can also be reused in the synthesis. Hence, this one-pot three component cost-effective protocol has been established as an invariable source for the synthesis of naphtha [1,2-e] oxazinones. Chitosan’s insolubility, bifunctionality and thermal stability and reusability have elevated its potentiality as heterogeneous catalyst in this protocol.
Key words: Naphtha-oxazinones, One-pot reaction, Chitosan, β-Naphthol, Urea, aldehydes
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