Original Research Article
Year: 2019 | Month: June | Volume: 6 | Issue: 6 | Pages: 199-202
Evaluation of Thyroid Functions in Severely Malnourished Children
Dr Sapna Gupta1, Dr Om Shankar Chaurasiya2
1Assistant Professor, Department of Pediatrics, MLB Medical College Jhansi.
2Associate Professor, Department of Pediatrics, MLB Medical College Jhansi.
Corresponding Author: Dr Om Shankar Chaurasiya
ABSTRACT
Background: Protein energy malnutrition (SAM) continues to be a major public health problem in the tropical and subtropical region of the world. It affects several aspects of secretion and metabolism of thyroid hormones. The present study has been conducted to study the effect of SAM on thyroid hormone.
Objective: To study the level of T3 , T4, TSH in severely malnourished children and healthy control.
Design: Case control study.
Setting: Nutritional rehabilitation centre in M.L.B medical college Jhansi.
Methods: The sample size consists of severely malnourished children between the age group of 6 months to 60 months. There were total 40 cases. Details were collected in predesigned proforma. Triiodothyronine (T3), thyroxine (T4), thyroid stimulating hormone (TSH) levels was estimated. The parameters were compared among cases and controls using appropriate statistical tool.
Results: T3 and T4 levels were significantly low in SAM children as compared to controls. TSH levels were similar in both groups.
Conclusions: Severe acute malnutrition (SAM) is associated with reduction in T3 and T4 levels without any alteration in TSH levels. The altered thyroid hormone status in children with PEM is perhaps a protective phenomenon to limit protein catabolism and lower energy requirements.
Key words: Severe Acute Malnutrition, Thyroxine, Triiodothyronine, Thyroid stimulating hormone.
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