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Original Research Article

Year: 2021 | Month: December | Volume: 8 | Issue: 12 | Pages: 323-327

DOI: https://doi.org/10.52403/ijrr.20211240

Evaluation of In-Vitro Anti-Inflammatory Activity of Gallic Acid

Raksha Agrawal¹, Aditya Ganeshpurkar¹, Megha Verma², Pradeep Golani², Devendra Singh Lodhi², Namarta Jain²

¹Shri Ram Institute of Technology Pharmacy Jabalpur M.P-482003 India
²Gyan Ganga Institute of Technology & Sciences, Bargi hills Jabalpur M.P-482003 India

Corresponding Author: Raksha Agrawal

ABSTRACT

Gallic acid's anti-inflammatory effect was studied at various concentrations, including 50,100,150,200, and 250 ug/ml. Gallic acid's anti-inflammatory effect was assessed using two in-vitro assays: proteinase inhibition and albumin denaturation. The greatest proteinase inhibition activity of 52.83 percent was achieved at a concentration of 250ug/ml, according to the results. It also revealed that at 250ug/ml, the maximum percentage inhibition in albumin denaturation was 74.79 percent. Gallic acid's antiproteinase and albumin denaturation activities both increase with increasing concentrations, according to this research.

Keywords: Gallic acid, Anti-Inflammatory, In-Vitro Assays, Albumin Denaturation, Proteinase activity.

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