Year: 2023 | Month: November | Volume: 10 | Issue: 11 | Pages: 460-464
DOI: https://doi.org/10.52403/ijrr.20231153
Characteristics And Complications of Patients with Parkinson's Disease at Sanglah General Hospital from November 2020 - November 2021
Fuji Restu Firma1, Sri Yenni Trisnawati2, Dewa Putu Gde Purwa Samatra2
1Neurology Resident, Faculty of Medicine Universitas Udayana, Sanglah General Hospital, Denpasar, Bali
2Neurologist, Faculty of Medicine Universitas Udayana, Sanglah General Hospital, Denpasar, Bali
Corresponding Author: Fuji Restu Firma
ABSTRACT
Background: Parkinson's disease is a neurodegenerative disease characterized by progressive loss of dopaminergic neurons that occurs over the years. Neurological disorders are the main causes of disability in the world, and Parkinson's disease is one of the fastest growing diseases. The prevalence of the disease ranged from 100 to 200 per 100,000 people and the annual incidence is estimated at 15 per 100,000.
Method: This research is a retrospective descriptive study. This research was conducted based on data from medical records from inpatient installations at Sanglah General Hospital, Denpasar from November 2020 – November 2021 with a sample size of 36 cases. The inclusion criteria are medical record data which contains information regarding research variables, such as gender, age, stage of disease, length of time diagnosed, therapy and complications.
Results: A total of 36 patients with Parkinson's disease in the inpatient installation at Sanglah Hospital, Denpasar. There were 23 male patients (63.9%) and 13 female patients (36.1%) (ratio 1.5:1). There were 4 people aged ≤55 years old (11.1%), 8 people aged 55-65 years old (22.2%), 13 people aged 65-75 years old (36.1%) and 11 people aged >76 years old (30.6%). Hoehn and Yahr stage I were 1 person (2.7%), stage II were 5 people (13.9%), stage III were 3 people (8,3%), stage IV were 12 people (33%) and stage V were 15 people (41.7%). The combination therapies of levopar, pramipexole and trihexilfenidil were administered in 9 people (25%), Levopar and Pramipexole were 7 people (19.4%) Levopar and Trihexilfenidil were 6 people (16.7% ), Levopar only were 4 people (11.1%) and other therapy were 10 people (27%). The duration of diagnosis was <5 years for 24 people (66.7%) and >5 years in 12 people (33.3%). The most common complications in patients were pneumonia in 21 people (58.3%), hyponatremia in 6 people (16.7%), immobilization in 3 people (8.3%), and no complications in 6 people (16.7%).
Conclusion: Parkinson's disease is more common in men than in women. The most common age group was 65-75 years old. The highest number of Hoehn and Yahr staging was stage V. Therapy for most patients was the combination of 3 drugs, namely levopar, pramipexole and trihexyphenidyl. The most common duration of diagnosis was <5 years. And the most common complication in patients was pneumonia.
Keywords: Parkinson's disease, neurodegenerative disease, Sanglah General Hospital.
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