Year: 2023 | Month: December | Volume: 10 | Issue: 12 | Pages: 312-323
DOI: https://doi.org/10.52403/ijrr.20231234
Overview of COVID-19 Vaccine Adverse Events Following Immunization in Bali
Sang Ayu Putu Damaghita Laverda Suri1, Desak Ketut Ernawati2, Bagus Komang Satriyasa3, Ni Wayan Sucindra Dewi4
1Bachelor of Medicine, 2,3,4Department of Pharmacology,
Faculty of Medicine, Udayana University, Denpasar, Bali, Indonesia
Corresponding Author: Sang Ayu Putu Damaghita Laverda Suri
ABSTRACT
Adverse event following immunization (AEFI) is undesired medical events that occur post-vaccination without considering whether there is a cause-and-effect relationship with the use of the vaccine or not. COVID-19 vaccination is an ongoing vaccination but the AEFI research is still limited, especially in Bali. This study aimed to report the overview of COVID-19 vaccine AEFI in Bali during January 2021 – December 2022. This was a descriptive study with cross-sectional approach by using the recapitulation data of the COVID-19 vaccine AEFI reports from the Bali Provincial Health Service. Of 958 cases, AEFI cases of COVID-19 vaccine were dominated by females (61.38%), age group of 18 – 29 years (38.73%), and domiciled in Denpasar (38.62%). The majority of adverse reaction reports were obtained from the hospital (53.34%), post vaccination of Sinovac (41.34%), and after the first dose (68.72%). The most frequently reported COVID-19 vaccine AEFI cases were non-serious AEFI (94.57%) with the most common symptoms in the local reaction group was pain at the injection site (9.65%), in the systemic reaction group was fever (17.77%), and in the other reaction group was shortness of breath (1.79%). In conclusion, AEFI of COVID-19 vaccine in Bali was dominated by females, age 18 – 29 years, and domiciled in Denpasar with most reports obtained from hospitals, post-vaccination of Sinovac, and after the first dose. The most reported AEFI cases were non-serious AEFIs where the most common symptoms were pain at the injection site for local reactions, fever for systemic reactions, and breathing difficulty for other reactions.
Keywords: COVID-19 vaccine, AEFI, side effect, adverse event
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