Case Report
Year: 2023 | Month: July | Volume: 10 | Issue: 7 | Pages: 460-465
DOI: https://doi.org/10.52403/ijrr.20230756
Cognitive Impairment in Patient with Fahr’s Syndrome Related to Hypoparathyroidism: A Case Report and Literature Review
Richard Suherlim, AAA Putri Laksmidewi, AAA Meidiary, Sri Yenni Trisnawati GS
Department of Neurology, Faculty of Medicine, Universitas Udayana, Prof. Dr. IGNG Ngoerah General
Hospital, Denpasar, Bali Indonesia
Corresponding Author: AAA Putri Laksmidewi
ABSTRACT
Fahr's syndrome is a very rare neurological disease, in which there is symmetrical and bilateral abnormal calcium deposit in brain areas such as basal ganglia, thalamus, cerebral cortex, subcortical, and hippocampus. Based on epidemiological studies, prevalence of Fahr’s syndrome is less than 1 case per 1 million. Fahr's syndrome can be caused by a variety of conditions, the most common of which is hypoparathyroidism. This article reports a 51-year-old female patient with seizures and cognitive impairment in the memory and visuospatial domains with Fahr’s syndrome associated with hypoparathyroidism caused by complication of her previous thyroidectomy. This is thought to be caused by the presence of calcifications in areas that interfere with neuronal function and also decreased glucose metabolism in these areas. It is important for the patient and family to know the disease. In addition to pharmacotherapy, education to the patients and their families is also very important. They have to do regular check-ups to evaluate the occurrence of long-term complications of Fahr's syndrome.
Keywords: Fahr’s syndrome, cognitive impairment, hypoparathyroidism, seizure
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