Year: 2024 | Month: December | Volume: 11 | Issue: 12 | Pages: 14-24
DOI: https://doi.org/10.52403/ijrr.20241203
The Role of Immunotherapy in the Management of Food Allergy
Yugo Berri Putra Rio1, Dwitya Elvira2
1Department of Internal Medicine, Faculty of Medicine Universitas Andalas/ RSUP DR. M. Djamil Padang, Padang, Indonesia.
Corresponding Author: Yugo Berri Putra Rio
ABSTRACT
Food allergy is a health disorder that results from a specific immune response to food. According to the World Allergy Organisation (WAO), 22% of the world's population suffers from allergies, and this number is increasing every year. The increasing morbidity and mortality rates of food allergy cases highlight the need for accurate diagnosis and appropriate treatment. Advances in science and technology have enabled a paradigm shift in allergy prevention, moving from allergen avoidance to desensitisation and active induction of immunological tolerance (immunotherapy). Immunotherapy for food allergy can utilise various routes of administration, including subcutaneous (SCIT), oral (OIT), sublingual (SLIT), intralymphatic (ILIT), and epicutaneous (EPIT). Currently, there are newer formulation approaches that modify the activity of the allergen, improving safety while maintaining effectiveness. The principle of immunotherapy involves gradually increasing exposure to specific allergens, resulting in desensitisation or increased tolerance to these allergens. This article aims to determine the role of immunotherapy in the management of food allergy.
Keywords: Food Allergy, Immunotherapy, Desentization
[PDF Full Text]