Year: 2024 | Month: March | Volume: 11 | Issue: 3 | Pages: 79-84
DOI: https://doi.org/10.52403/ijrr.20240310
Effectiveness of Lemongrass Leaf Ethanol Extract Spray Preparation in Inhibiting the Growth of Diabetic Ulcer Isolate MRSA Bacteria
Ariffialdi Nurhidayattulloh1, Khoirul Rista Abidin2, Edy Suwandi3
1,2Aisyiyah Polytechnic Pontianak, 3Ministry of Health Polytechnic Pontianak, West Kalimantan, Indonesia
Corresponding Author: Ariffialdi Nurhidayattulloh
ABSTRACT
Lemongrass (Cymbopogon nardus) is a type of grass from the order Graminales which is typical of tropical areas of Asia. Compounds contained in lemongrass leaves can inhibit the growth of Methicillin Resistant Staphylococcus aureus (MRSA) bacteria. This research aims to determine the effectiveness of spray preparations of lemongrass leaf extract in inhibiting the growth of MRSA bacterial isolates from diabetic ulcers.
The research design of this study is quasi experimental. Data obtained from primary data by testing the inhibitory power of spray preparations against MRSA bacteria. The results obtained were analyzed using the One Way Anova statistical test.
The diameter of the inhibition zone for MRSA bacteria in the 25% concentration ethanol extract spray preparation was 4 mm, the 35% concentration was 7 mm, the 45% concentration was 11 mm and the antibiotic Vancomycin was 12 mm. There are differences in the inhibition zone of spray preparations of ethanol extract of lemongrass leaves with concentrations of 25%, 35%, 45% and the antibiotic disc vancomycin with p value = 0.00 < α 0.05.
Spray preparations of ethanol extract of lemongrass leaves with concentrations of 25%, 35% and 45% are not effective in inhibiting the growth of Methicillin Resistant Staphylococcus aureus (MRSA) bacteria, however, the average zone of inhibition for spray preparations with ethanol extract of lemongrass leaves with a concentration of 45% is against MRSA bacteria. 11 mm is included in the strong category.
Keywords: Lemongrass Leaves, MRSA Bacteria, Spray preparation.
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