Year: 2024 | Month: May | Volume: 11 | Issue: 5 | Pages: 157-159
DOI: https://doi.org/10.52403/ijrr.20240519
A Complex Case of Colchicine-Induced Myopathy and Polyarticular Gout in a Patient with Chronic Kidney Disease
Ananthan J1, Nihal Muhammed1, Shaju S Dharan2, Dhanya Dharman3
1Pharm D Intern, Department of Pharmacy Practice, Ezhuthachan College of Pharmaceutical Sciences, Marayamuttom, Thiruvananthapuram, Kerala
2Principal/HOD, Department of Pharmacy Practice, Ezhuthachan College of Pharmaceutical Sciences, Marayamuttom, Thiruvananthapuram, Kerala
3Associate Professor, Department of Pharmacy Practice, Ezhuthachan College of Pharmaceutical Sciences, Marayamuttom, Thiruvananthapuram, Kerala
Corresponding Author: Dhanya Dharman
ABSTRACT
Colchicine, a medication commonly used for the treatment of gout and other inflammatory conditions, is known to cause various adverse effects, including myopathy. We present a case of colchicine-induced myopathy in a 58-year-old male with a history of gout. The patient developed progressive muscle weakness after initiating colchicine therapy. Prompt discontinuation of colchicine resulted in resolution of symptoms and normalization of muscle enzyme levels. This case underscores the importance of recognizing colchicine-induced myopathy and prompt discontinuation of the medication to prevent further complications and report also highlights the challenges and considerations in managing a patient with multiple comorbidities and the importance of close follow-up and ongoing monitoring.
Keywords: Colchicine, Myopathy, Gout, Adverse effects, Muscle weakness
[PDF Full Text]