Year: 2024 | Month: June | Volume: 11 | Issue: 6 | Pages: 631-635
DOI: https://doi.org/10.52403/ijrr.20240669
Helicobacter Pylori Associated Gastritis: Case Series
Adithya S L1, Shaiju S Dharan2, Bincy Babu*, Dhanya Dharman3
1Pharm D Intern, Ezhuthachan College of Pharmaceutical Sciences, Marayamuttom, Thiruvananthapuram, Kerala, India
2Principal, HOD, Department of Pharmacy Practice, Ezhuthachan College of Pharmaceutical Sciences, Marayamuttom, Thiruvananthapuram, Kerala, India
*Assistant Professor, Department of Pharmacy Practice, Ezhuthachan College of Pharmaceutical Sciences, Marayamuttom, Thiruvananthapuram, Kerala, India
3Associate Professor, Department of Pharmacy Practice, Ezhuthachan College of Pharmaceutical Sciences, Marayamuttom, Thiruvananthapuram, Kerala, India
Corresponding Author: Dr Bincy Babu
ABSTRACT
Helicobacter (H. Pylori) infection is a common habitual infection responsible for upper gastrointestinal symptoms such as indigestion, abdominal pain, spewing, heart burn, and abdominal wholeness along with nausea and vomiting [1]. H Pylori is a mortal pathogen. The primary complaint associated with this infection is habitual active gastritis. The inflammation can lead to peptic ulceration and atrophic gastritis in a considerable number of infected subjects. A minority eventually develops gastric cancer or tumour. The threat of similar complications depends upon the inflexibility of gastritis, which is determined by various host and bacteria related factors. Among bacterial factors, the common one is the cagA pathogenicity, the presence of which has been associated with more severe gastritis, peptic ulceration, atrophic gastritis and gastric cancer [2]. Among the host factors, most of the evidence focuses on acid production in response to H. Pylori infection. To confirm the pathogenic part of H. Pylori, both the existent’s histological features of habitual gastritis and topographical patterns must be shown to be caused by the infection. Surface epithelial degeneration is a probable result of direct tissue injury by bacteria. Here are four intriguing cases of H. Pylori positive patients who had different admission presentations and were successfully treated with first line remedy and salvage remedy.
Keywords: H. Pylori, PUD, gastritis, gastric cancer
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