Year: 2025 | Month: December | Volume: 12 | Issue: 12 | Pages: 734-738
DOI: https://doi.org/10.52403/ijrr.20251275
The Dynamic Relationship Between the Ovaries and Endometrium and Its Connection to Ovarian Cancer
Siti Mirhalina Hasibuan1, Dani Sapawi2, Lutfiah Ramadani3, Hasrina Putri4
1,2,3,4Department of Medicine and Health Sciences, Universitas Muhammadiyah Sumatera Utara, Indonesia
Corresponding Author: Siti Mirhalina Hasibuan
ABSTRACT
The menstrual cycle is a complex process involving a dynamic interaction between the ovaries and the endometrium, essential for egg maturation and the preparation of the uterine lining for implantation. Disruptions in this interaction, as seen in Polycystic Ovary Syndrome (PCOS), can increase the risk of ovarian cancer, where hormonal imbalances and insulin resistance lead to endometrial dysfunction. Furthermore, factors such as psychological stress and infections can also disrupt the menstrual cycle and trigger systemic inflammation associated with an increased risk of ovarian cancer. Understanding these dynamics is crucial for reproductive health and the prevention of ovarian cancer.
Keywords: Menstrual Cycle, Ovary, Endometrium, Ovarian Cancer, PCOS.
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