Year: 2025 | Month: December | Volume: 12 | Issue: 12 | Pages: 897-902
DOI: https://doi.org/10.52403/ijrr.20251289
Association Between Serum Calcium with Pancreatic Enzymes and Serum Albumin in Chronic Kidney Disease; A Case Control Study
Sanju Negi1, Dr. Shreya Nigoskar2
1PhD Research Scholar, Department of Biochemistry, Index Medical College hospital & Research Centre, Malwanchal University, Indore (MP)
2Professor & Head, Department of Biochemistry, Index Medical College hospital & Research Centre, Malwanchal University, Indore (MP)
Corresponding Author: Sanju Negi
ABSTRACT
Background: CKD involves a gradual loss of kidney function over a period of three or more months with or without kidney damage. Diabetes and HTN are the leading causes of CKD.CKD patients may have malnutrition, anemia, pancreatic and mineral bone disorders that can affect the bones, heart and blood vessels of person with CKD. Estimation of SA, SL, calcium and albumin remains the main method of diagnosing these conditions.
Aims & Objectives: To find out the association between serum calcium with serum amylase, serum lipase and serum albumin in CKD and non-CKD patients.
Methodology: Case-Control Study, conducted in Department of Biochemistry, Index Medical College, Hospital & Research Centre Indore, Madhya Pradesh, during a period of 24 months. 100 patients of CKD as case and 100 age and sex matched persons included as control. Cases were selected as per inclusion and exclusion criteria. A pre-tested questionnaire based on semi- structured proforma was used to collect the data including basic profile of participants. chi-square Test, Pearson’s coefficient was used to find the association between Pancreatic enzymes, Sr. Calcium and Sr. Albumin in patients of CK.
Result: Out of 100 cases and 100 controls ,55.5% were males and 44.5% were female. a positive correlation between SA and serum calcium in Case while negative correlation found between SA and serum calcium in Controls was found, although not significant. (p>0.05). A significant positive correlation between Sr. calcium and serum albumin in Case and Control was found. A significant but negative correlation between Sr. calcium and SL in Case while a significant positive correlation between Sr. calcium and SL in Control was found.
Conclusion: estimation of Serum calcium, serum amylase, lipase and albumin is important for treatment and progression of CKD.
Keywords: Association, pancreatic enzymes, albumin, serum calcium
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