Year: 2026 | Month: January | Volume: 13 | Issue: 1 | Pages: 94-103
DOI: https://doi.org/10.52403/ijrr.20260110
The Synergistic Potential of Copper Nanoparticles and Saccharum Officinarum Phytochemicals in the Modulation of Neurodegeneration in Parkinson’s Disease: Insights from Siddha Inspired Approach
Shanmugam. M*1, S.Balamani2, S. Sulfin Nihar3
*1PG Scholar, Department of Toxicology, Govt. Siddha Medical College, Palayamkottai.
2Associate Professor, Department of Toxicology, Govt. Siddha Medical College, Palayamkottai.
3Head of the Department, Department of Toxicology, Govt. Siddha Medical College, Palayamkottai.
Corresponding Author: Shanmugam. M mshanmugamsmnk@gmail.com
ABSTRACT
Parkinson’s disease (PD) is a neurodegenerative disorder marked by oxidative stress, neuroinflammation, and α-synuclein aggregation, leading to dopaminergic neuron loss. This study explores the therapeutic potential of copper nanoparticles (CuNPs) and Saccharum Officinarum phytochemicals, leveraging their antioxidant and neuroprotective properties. Analyses of articles revealed that CuNPs reduce oxidative stress, inhibit α-synuclein aggregation, and downregulate pro-inflammatory cytokines, improving motor function and neuron survival. Combining Siddha medicine with nanotechnology, CuNPs show promise as a PD treatment. Further research is needed to optimize clinical applications and delivery methods for enhanced therapeutic efficacy.
Keywords: Copper nanoparticles (CuNPs), Saccharum Officinarum, Parkinson’s Disease, Siddha Medicine..
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