Year: 2026 | Month: March | Volume: 13 | Issue: 3 | Pages: 194-197
DOI: https://doi.org/10.52403/ijrr.20260323
Pyogenic Granuloma Mimicking Oral Malignancy in a Midline Diastema: A Case Report
Preetha. D1, Nagasurthi. K J2, Arunmozhi. U3
1Postgraduate Student, Department of Periodontology and Oral Implantology, Sri Venkateswara Dental College and Hospital, Chennai, Tamil Nadu, India, Pincode-600130,
2Postgraduate Student, Department of Periodontology and Oral Implantology, Sri Venkateswara Dental College and Hospital, Chennai, Tamil Nadu, India, Pincode-600130,
3HOD and Professor, Department of Periodontology and Oral Implantology, Sri Venkateswara Dental College and Hospital, Chennai, Tamil Nadu, India, Pincode-600130,
Corresponding Author: Nagasurthi. K J
ABSTRACT
Pyogenic granuloma is a benign reactive vascular lesion commonly affecting the oral cavity, particularly the gingiva. Although the diagnosis is usually straightforward, certain clinical presentations may closely resemble malignant lesions and pose a diagnostic challenge. This report describes a 58-year-old female who presented with a rapidly enlarging, ulcerated, bleeding gingival growth located in the midline diastema region. The lesion exhibited aggressive clinical features, raising suspicion of oral malignancy. The patient had a history of prolonged amlodipine use for hypertension. Histopathological evaluation confirmed the diagnosis of lobular capillary hemangioma type of pyogenic granuloma. The lesion was managed by complete surgical excision with curettage, followed by reinforcement of oral hygiene measures and medical consultation. Healing was satisfactory, and no recurrence was observed during a 6-month follow-up period. This case highlights the importance of careful clinical assessment and histopathological confirmation when managing gingival lesions with malignant-like features.
Keywords: Pyogenic granuloma; Midline diastema; Amlodipine; Oral malignancy mimic; Drug-induced gingival lesion
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