Year: 2026 | Month: June | Volume: 13 | Issue: 6 | Pages: 474-479
DOI: https://doi.org/10.52403/ijrr.20260646
Insulin Secretion and Meda Dhatu: Neuroendocrine Integration in Ayurveda
Divya Khinchi1, Prof. Ashok Kumar Sharma2, Prof. Kishori Lal Sharma3
1PG Scholar, Madan Mohan Malviya Government Ayurved College, Udaipur
2Prof & H.O.D., Madan Mohan Malviya Government Ayurved College, Udaipur
3Professor, Madan Mohan Malviya Government Ayurved College, Udaipur
.
Corresponding Author: Divya Khinchi
ABSTRACT
Background: The increasing global prevalence of metabolic disorders such as obesity, insulin resistance, metabolic syndrome, and type 2 diabetes mellitus has directed scientific attention toward the neuroendocrine regulation of metabolism. Modern biomedical sciences recognize insulin as a pivotal anabolic hormone controlling glucose homeostasis, lipid metabolism, appetite regulation, and cellular energy utilization. Ayurveda, through its sophisticated understanding of Meda Dhatu, Agni, Kapha Dosha, Srotas, and neuropsychological regulatory mechanisms, provides a multidimensional explanation for metabolic balance and disease progression. Although classical Ayurvedic texts do not explicitly mention insulin, the functional attributes of insulin closely resemble the physiological activities governing Meda Dhatu metabolism and nourishment.
Aim: This article aims to critically explore the relationship between insulin secretion and Meda Dhatu through the lens of neuroendocrine integration in Ayurveda and correlate Ayurvedic principles with modern endocrinology and neurophysiology.
Materials and Methods: Classical Ayurvedic literature including Charaka Samhita, Sushruta Samhita, and Ashtanga Hridaya was conceptually reviewed along with contemporary biomedical literature related to insulin physiology, neuroendocrine regulation, adipose tissue biology, hypothalamic pathways, and metabolic homeostasis.
Discussion: Ayurveda describes Meda Dhatu as a dynamic tissue involved not only in fat storage but also in lubrication, energy preservation, structural stability, hormonal balance, and metabolic buffering. Insulin secretion is influenced by neuroendocrine pathways involving the hypothalamus, autonomic nervous system, gut hormones, and psychological stress. These mechanisms parallel Ayurvedic concepts such as Manovaha Srotas, Majja Dhatu, Prana Vayu, Samana Vayu, Pachaka Pitta, and Kledaka Kapha. Dysregulation of these integrative networks leads to Medodushti, Agnimandya, Aama formation, and ultimately metabolic disorders including Prameha.
Conclusion: The Ayurvedic understanding of Meda Dhatu offers a comprehensive framework for interpreting insulin physiology and neuroendocrine metabolism. Integrative exploration of insulin secretion through Ayurvedic principles may contribute significantly toward holistic management strategies for obesity, diabetes, and stress-induced metabolic disorders.
Keywords: Insulin, Meda Dhatu, Neuroendocrine Integration, Ayurveda, Prameha, Agni, Kapha, Metabolic Syndrome, Obesity, Neurophysiology.
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