Original Research Article
Year: 2018 | Month: November | Volume: 5 | Issue: 11 | Pages: 111-118
Study of Drug Compliance and Its Influencing Factors in Schizophrenic Patients
Keerthi Chandana Veera1, Jayadivya Paravada1, Bala Subrahmanyam Simhadri1, Tirumala Deepthi Repalle1, Nageswara rao Samidala2, Niveditha Vasireddy3
1Pharm. D Intern, Department of Pharmacy Practice, Aditya Pharmacy College, Surampalem, AP, India.
2Associate Professor, Department of Pharmacology, Aditya Pharmacy College, Surampalem, AP, India.
3Assistant Professor, Department of Psychiatry, R.M.C/G.G.H, Kakinada.
Corresponding Author: Keerthi Chandana Veera
ABSTRACT
The aim was to study drug compliance & to identify factors influencing with compliance in schizophrenic patients. 70 subjects (consecutive sampling) meeting the inclusion criteria were included and details were collected in the Structured Socio demographic Proforma. The MARS scale was administered first followed by ROMI and PANSS scales. Risk factors affecting compliance were analysed using Chi-square (χ2) test. Independent t-test was performed to assess severity of illness by comparing MARS scores & ROMI scores with the PANSS scores. The results of the study showed that 56% were compliant & 44% were noncompliant. Majorities were belonged to the female gender & the compliance rate was higher among the females (54%). The level of significance was taken at p<0.05. Substance abuse was a strong predictor of non-compliance. Statistically, significant association was found between substance abuse and compliance (p<0.05). Highly statistical significant association was found in both Reasons for compliance (p<0.0001) & noncompliance questions (p<0.05) under ROMI scale. There was a statistically significant association between drug compliance and its influencing factors. Clinicians should maintain a positive relationship with patients to counsel them about drug compliance & to reduce the burden and chronicity of schizophrenia.
Key words: Adherence, Compliance, Schizophrenia, Severity of illness, Sociodemographic factors.
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