Original Research Article
Year: 2018 | Month: December | Volume: 5 | Issue: 12 | Pages: 239-242
Correlation of Clinical Diagnosis of Perinatal Asphyxia and Severity of HIE with Spot Urinary Uric Acid to Creatinine Ratio
Vineet Popli1, Shakti Datt Sharma2
1Department of Pediatrics, 2Department of Anesthesiology,
Dr. BSA Hospital, Rohini, New Delhi, India.
Corresponding Author: Shakti Datt Sharma
ABSTRACT
Retrospective diagnosis of perinatal asphyxia is an important challenge in country like India where nearly two-thirds of the child births are unsupervised and neonates with perinatal asphyxia are brought to hospital without any reliable perinatal history. The overlapping of signs and symptoms of perinatal asphyxia with various other conditions make the diagnosis more difficult. Mostly diagnosis is by clinical assessment and severity is assessed by SARNAT an SARNAT staging. This study was carried out in Dr. BSA Hospital and Medical College in 2016 using simple biochemical test UUA/Cr for assessing severity of HIE. This is a simple and readily available test in most of the hospitals. We found this test as a very useful biochemical marker for diagnosis of perinatal asphyxia and staging severity of HIE. There was a significant correlation between ratio of UUA/Cr to severity of HIE.
Key words: HIE- hypoxic ischemic encephalopathy, AGA- appropriate for gestational age, FT- full term, UUA/Cr-Urinary Urinary Uric Acid to Creatinine ratio, APGAR score, NST-Non-reactive stress test, TMSAF-thick meconium stained amniotic fluid, LSCS-lower segment caesarian section, SNART and SNART staging of HIE
[PDF Full Text]