Original Research Article
Year: 2018 | Month: December | Volume: 5 | Issue: 12 | Pages: 342-348
To Study the Risk Factors Associated with Early Onset versus Late Onset Preeclampsia and Its Fetomaternal Outcome
Karuna Kanta Das, Manoj Kumar Majumdar, Sanskriti Rajkumari
Department of Obstetrics and Gynaecology, Gauhati Medical College and Hospital, Guwahati, Assam
Corresponding Author: Sanskriti Rajkumari
ABSTRACT
Objectives: a) To identify the different risk factors in early onset and late onset Preeclampsia. b) To compare the Fetomaternal outcomes in both the groups.
Study design: This was a one year cross-sectional study conducted in the Department of Obstetrics and Gynaecology at Gauhati Medical College and Hospital. 200 mothers with Preeclampsia were taken and 100 were grouped into Early onset preeclampsia (EO-PE) (<34 weeks of gestation) and another 100 into Late onset preeclampsia (LO-PE) (≥34 weeks of gestation). Data about maternal risk factors, maternal complications, foetal and neonatal outcome were analysed and statistical significance determined.
Results: Primiparity, increasing BMI, family history of preeclampsia and male sex of the foetus were found to be important risk factors in development of EO-PE. All the maternal complications like eclampsia, sepsis, systemic disorders, ICU admissions and maternal deaths were higher in EO-PE as compared to LO-PE. Greater number of patients with EO-PE progressed to develop severe preeclampsia. The rate of neonatal complications like abnormal umbilical artery Doppler, low birth weight, reduced APGAR score was higher in EO-PE. Incidence of NICU admissions and neonatal/perinatal deaths was also noted to be higher in EO-PE.
Conclusion: Classification of preeclampsia into early and late onset has both etiological and prognostic value. Early detection, close monitoring, timely intervention by the obstetrician and good neonatal care by the paediatrician is the key for successful outcome in both Early onset and Late onset preeclampsia.
Key words: Early onset preeclampsia, Late onset Preeclampsia, Maternal, neonatal outcome, risk factors and outcome.
[PDF Full Text]