Original Research Article
Year: 2018 | Month: April | Volume: 5 | Issue: 4 | Pages: 12-20
Variation of Stone Composition According to Gender and Age: Our Experience in a Tertiary Care Centre in North East India
Prof Rajeev T.P1, Dr. Nabajeet Das2, Dr. Pranab Kumar Kaman2, Dr. Sasanka Kumar Barua3,
Dr. Debanga Sarma4
1Professor, 2Trainee, 3Associate Professor, 4Assistant Professor,
Dept of Urology and Renal Transplantation, Gauhati Medical College Hospital, Guwahati, India
Corresponding Author: Dr. Nabajeet Das
ABSTRACT
Introduction and Objective: Calcium oxalate constitutes around 60%, mixed calcium oxalate and hydroxyapatite 20%; and brushite 2%. Both uric acid and struvite stones are seen in 10%. The male to female ratio is found to be 3:1. Peak incidence is seen in 4th to 6th decade. Objective of this study is to study the variation of stone composition according to gender and age in this region.
Materials and Methods: In this retrospective study a total of 150 patients, who were being operated for renal stone disease, were analysed for calcium oxalate monohydrate (COM) , calcium oxalate dihydrate (COD), carbonate apatite (CA), uric acid containing stones (U) and magnesium ammonium phosphate (MAP). Gender and age were taken as the demographic variables with which stone composition are being statistically compared.
Results: Male to female ratio was 2.75:1. Mean age at presentation was 42.89 years. Composition according to gender are COM (M-58%, F-62%), COD (M-22.27%, F- 21.25%), Uric acid stones (M- 13%, F- 4.5%), CA (M- 6.55%, F- 11%) and MAP (M- 0.18%, F- 0). Relative percentage of stone composition varied in different age groups. COM decreased with age, urate increased with age and carbonate apatite remained the same. The incidences of stone composition in male patients among the various age groups showed that COM slightly decreased with age and uric acid component increased with age.
Conclusion: The variation in stone composition according to gender in this study was not statistically significant. However, the stone composition (Calcium oxalate, uric acid and carbonate apatite) varied significantly with age.
Key words: stone composition, gender, age, northeast India.
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