Case Report
Year: 2018 | Month: August | Volume: 5 | Issue: 8 | Pages: 57-59
Vancomycin Induced Exanthem- A Case Report
Dr. S. Parveen1, S. Deva sree2, K. Bhargavi2, Ch. Ascharya2, A.V. Kavya sree2
1Assistant Professor, 2Pharm D Interns,
Department of Pharmacy Practice, P. Rami Reddy Memorial College of Pharmacy, JNTUA, RIMS Hospital, Kadapa, Andhra Pradesh, India.
ABSTRACT
Exanthem is a skin eruption, as a prominent manifestation accompanying certain infectious diseases. It is an acute, short lived, viral disease of infants and young children characterized by high fever at onset that drops to normal after 3-4 days and concomitant appearance of a maculo popular rash that appears first on trunk and then spreads to other areas. Exanthem is widely spread out rash which is caused due to underlying diseases, heat rash, sun burn, toxins, viruses and medication side effects. It is one of the major side effects associated with the use of parenteral Vancomycin especially in the department of Pediatrics.
Vancomycin is an antibiotic used to treat number of bacterial infections. It is complex tricyclic glycopeptide antibiotic obtained from Nocardia species Amycolatopsis orientalis. Vancomycin has strong bactericidal activity against a broad range of gram positive bacteria. With the increase in vancomycin use, adverse drug reactions (ADRs) associated with vancomycin have been reported increasingly more often. However, the characteristics of cutaneous ADRs with and without systemic reactions (SRs) have not been described.
We are reporting a case of 3 months old male child with complaints of fever which is continuous in nature, improper feed intake and continuous crying. The child was diagnosed as a case of SEPSIS based on laboratory data. During the course of treatment the child developed exanthem after administration of parenteral Vancomycin. So Vancomycin was withdrawn and alternatively parenteral Taxim and Calamine and Diphenhydramine HCL lotion was prescribed to treat Exanthem.
Key words: Vancomycin, Exanthem, Sepsis.
[PDF Full Text]