Original Research Article
Year: 2019 | Month: November | Volume: 6 | Issue: 11 | Pages: 237-244
Role of MRI in Evaluation of First Onset Epilepsy: Our Experience of 100 Patients
Dr Monika Sharma1, Dr Sanjeev Sharma2, Dr Harmeet Kaur1
1Assistant Professor, 2Associate Professor,
Department of Radio Diagnosis, Maharishi Markandeshwar Medical College and Hospital, Solan, Himachal Pradesh, India.
Corresponding Author: Dr Sanjeev Sharma
ABSTRACT
Background: MRI plays an important role for the accurate diagnosis in patients with epilepsy disorder. Accurate etiology and diagnosis of epilepsy is important for an effective medical or surgical management. MRI is the most sensitive and specific imaging technique for identification of epileptogenic substrates, based on imaging findings. The present study aims to find the spectrum of imaging findings of first onset epilepsy on MRI in developing country.
Material and methods: It is a prospective study, in which 100 cases of age group between 10-80 years were included, between August 2017 to June 2019 in our institute ( Maharishi, Markandeshwar Medical College and Hospital) and underwent MRI on machine (1.5 T) PHILIPS ACHEIVA system. MRI dedicated epilepsy protocol was performed to improve sensitivity and specificity to exclude structural abnormalities. Different MRI sequences used in epilepsy protocol were performed.
Results: Out of total 100 patients included in our study, 62 were males and 38 were females. The maximum patients were of 20-30 yrs and followed by 30-40 age groups. The MRI findings were normal in 34 cases and etiology could not be identified on MRI examination, therefore labeled as idiopathic. The most common MRI findings in the present study were of granulomatous etiology, which include neurocysticercosis and tuberculoma in our study, followed by gliosis/infarction and mesial temporal sclerosis. The unusual diagnosis was dysgenesis of corpus callosum, venous angioma, and tuber cinerum hamartoma.
Conclusion: MRI helps in early recognisation of treatable conditions of epilepsy, thus helps in timely management of the disease. MRI is the initial investigation of choice in seizure patients, because of its high diagnostic yield to identify epileptogenic substrates, its multiplanar capability and lack of ionizing radiation.
Key words: Brain MRI, Epilepsy, Neuroimaging, seizure, Magnetic resonance spectroscopy.
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