Review Article
Year: 2019 | Month: November | Volume: 6 | Issue: 11 | Pages: 570-580
Piperazine Derivatives: A Review of Activity on Neurotransmitter Receptors
Seba M C, Dr. S M Sandhya, Dr. Prasobh G R
Department of Pharmaceutical Chemistry, Sree Krishna College of Pharmacy and Research Centre, Parassala, Kerala, India
Corresponding Author: Seba M C
ABSTRACT
Piperazine is a vital organic scaffold that consists of a six-membered ring containing two nitrogen atoms at opposite positions in the ring and also posse’s four carbon atoms. This moiety can be found in surplus of well-known drugs with pharmacophoric activities on various receptors. Piperazine derivatives have been the subject of research for activity primarily on neurotransmitter receptors. This review focused on the activity of piperazine pharmacophore on diverse neurotransmitter receptors.
Key words: Piperazine, Pharmacophoric activities, Neurotransmitter receptors.
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