Changes in Serum Blood Sugar Levels before and After Induction of General Anaesthesia with Propofol and Thiopentone: An Observational Comparative Study Done In a Teaching Hospital

Rakesh Ranjan Singh¹, Ashmita Kiran²

¹Associate Professor, Department of Anaesthesia, ²Assistant Professor, Department of Gynaecology,
Katihar Medical College & Hospital, Karimbagh, Katihar, Bihar.

Corresponding Author: Rakesh Ranjan Singh

ABSTRACT

Aim: The main aim of the study was to evaluate the propofol and thiopentone used before and after induction of general anaesthesia and as a result its effect of its in serum blood sugar levels.
Material and Method: In this observational prospective study was conducted on120 patients who had admitted under surgery department and were categorised as ASA I & II. The entire population were again equally divided in two groups named Group A and Group B and each group were having 60 patients. Group A patients were received Thiopentone 5mg/kg body weight IV as initial loading dose and Group B patients were received Propofol 5mg/kg body weight IV as initial loading dose. As a primary outcome measurement a random blood glucose test was performed in both the groups after 5 minutes of initial IV.
Result: Both the group were almost identical in demographic parameters and it has been observed that Group B with Propofol were more effective than Group A with Thiopentone towards reduction in vital parameters like blood pressure (both SBP & DBP), PR and RPP in both cases that is after induction and 1,3,5,10 min after endotracheal intubation and along with that it has also observed that near the baseline or even bellow from that was the SBP, DBP and MAP in Group B where as it was above in case of Group A.
Conclusion: The study has concluded that before and after induction of general anaesthesia as compare to thiopentone, Propofol provides stable hemodynamic condition. Blood Sugar level which was measured as RBS was found to be significantly reduced in propofol group as compared to other thiopentone group of patients.

Key words: Propofol, Thiopentone, Serum Blood Sugar levels, General Anaesthesia.

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