Review Article
Year: 2019 | Month: December | Volume: 6 | Issue: 12 | Pages: 300-305
Factors Related to Polycystic Ovary Syndrome Among Women in Asia Population: A Systematic Review
Astri Dwi Andini1, Sylfia Mustika1, Rashif Hizbullah Arsya1, Ulfa Rahmi1, Nabilla Mustafa1, Risma Anjelina1, Ricvan Dana Nindrea2
1Faculty of Medicine, Universitas Andalas, Padang City, Indonesia
2Department of Public Health and Community Medicine, Faculty of Medicine, Universitas Andalas,
Padang City, Indonesia
ABSTRACT
Background: Polycystic ovary syndrome (PCOS) is the most common endocrine disturbance that affects 5-20% in women of reproductive age, and its etiology remains unclear, but it is widely unknown for different subpopulations based on geographical location and race/ethnicity. This study aimed to review factors related to polycystic ovary syndrome (PCOS) among women in Asia Population.
Methods: This systematic review was conducted on published research articles on factor related to polycystic ovary syndrome among women in Asia population. Impact factor is one measure showing the average citation for articles published by a scientific journal published between 2014 and 2019 on the online article database of PubMed. The data collected is an English language article with the type of article in the form of an original article. The articles that have been collected will be tabulated according to the name of the author, the year the paper was published, the location of the study, and the number of research samples and research was only limited to humans. Data were analyzed with narrative synthesis.
Results: A total of 209 articles have been reviewed, 4 of which have been selected for systematic review. The results showed the risk factors of polycystic ovary syndrome among Asian women are: insulin resistance (Asian women were more likely to have diabetes compared with Caucasian); hyperandrogenemia (total testosterone, androstenedione, and FAI secretion were increased in women with PCOS); genetics (the VDR gene BsmI A/G ApaI A/C TaqI T/C in South Indian women, constitute an inheritable risk factor for PCOS); and obesity (body mass index, waist circumference, and body fat percentage facilitating the screening or diagnosis of PCOS).
Conclusion: From the analysis, we found that the risk factors of polycystic ovary syndrome among Asia women are insulin resistance, hyperandrogenemia, genetics, and obesity.
Key words: Polycystic ovary syndrome, Asia, Insulin resistance, Hyperandrogenemia, Genetics, Obesity
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