Original Research Article
Year: 2019 | Month: March | Volume: 6 | Issue: 3 | Pages: 141-146
A Prospective Randomized Double Blind Study to Evaluate Efficacy of Intravenous Dexamethasone for Postoperative Sore Throat in Patients Undergoing Surgery under General Anesthesia
Dr Abida Yousuf1, Dr Aabid Hussain Mir1, Dr Sheikh Quyoom Hussain2, Dr. Showkat A. Gurcoo3, Dr. Sheikh Irshad4
1Senior Resident, 3Professor, 4Associate Professor,
Department of Anaesthesiology and Critical Care, SKIMS, Soura, Srinagar, India-190011
2Assistant Consultant, Department of Neonatology, King Saud Medical City, Riyadh, Saudi Arabia
Corresponding Author: Dr Aabid Hussain Mir
ABSTRACT
Background: administration of general anesthesia is associated with endotracheal intubation which in turn causes postoperative sore throat. Our aim was to see the effectiveness of intravenous dexamethasone in prevention of postoperative sore throat.
Methods: 100 patients of ASA physical status I and II in the age group of 18 to 70 years were divided into two groups of 50 each. Group I (dexamethasone group) received intravenous dexamethasone 8 mg in 50 mL normal saline for 10 minutes after intubation and group II (placebo group) received 50 ml of normal saline for 10 minutes after intubation. Incidence and severity of sore throat and incidence of hoarseness of voice was assessed at different study intervals postoperatively.
Results: There was statistically significant decrease in sore throat and hoarseness in dexamethasone group than placebo group (p-value<0.05).
Conclusion: Dexamethasone given intravenously reduces incidence and severity of sore throat and incidence of hoarseness caused due to endotracheal intubation.
Key words: Dexamethasone, sore throat, hoarseness, endotracheal intubation
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