Review Article
Year: 2019 | Month: June | Volume: 6 | Issue: 6 | Pages: 180-187
Breast Cancer Stem Cells Eradication: A Newer Approach towards the Treatment of Breast Cancer
Tiji. S.L, Sujitha .P.J, Sambathkumar. R
Department of Pharmacy Practice J.K.K.Nattraja College of Pharmacy, Kumarapalayam -638183, Tamil Nadu, India
Corresponding Author: Sujitha .P.J
ABSTRACT
Cancer is one of the major public health problems around worldwide, and the number of cancer cases increases every year and it was expected to reach 17.1 million by the year of 2020. Stem cells are known as the primal cells found in all multi-cellular organisms. They have the ability to renew themselves through mitotic cell division and can differentiate into a variety range of specialized cell types. Stem cell transplants are mainly used to replace bone marrow that has been destroyed by cancer or destroyed by the chemo and radiation therapy which is used to treat the cancer. Breast cancer remains the most common malignancy among women around the worldwide and more over, it is believed that cancer targeted therapies particularly stem cell targeted therapy are superior to current treatments such as traditional chemotherapy or radiotherapy inorder to overcome recurrence, metastasis and chemo-resistance. This review article details about the stem cells, normal human breast and stem cells application in treatment of breast cancer.
Key words: Breast cancer stem cells, cancer stem cells, Aldehyde dehydrogenase
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