Original Research Article
Year: 2019 | Month: July | Volume: 6 | Issue: 7 | Pages: 19-23
Role of Lipoprotein (a) In Coronary Artery Disease
Aruna Bhagat Dubey
Assistant Professor, MMIMSR, Mullana, Ambala
ABSTRACT
Objective: This study was a prospective case-control study to know lipoprotein(a) [Lp(a)] levels and its role as an independent risk factor in coronary artery disease in Jammu population of northern India. Study was done on a consecutive 100 subjects who underwent coronary angiography in Government Medical College, Jammu for a period of one year .
Method: Lp(a) was measured in serum samples by immunoturbidimetric assay by using commercial kit from Diasys Diagnostic Systems GmbH D-65558 Holzheim Germany. The data so obtained was statistically analyzed.
Result: The present study confirmed the evidence that Lp(a) > 30 mg/dl is an independent risk factor for IHD .In present study also, 88.3% of patients with IHD had Lp(a) levels between 26-75 mg/dl. For Lp(a) levels between 26-79 mg/dl, the risk of IHD increased by 15 times among IHD group. In this study, patients with myocardial infarction had higher levels of Lp(a) as compared to patients who had presented with angina. All the same, the study does give an important clue regarding the relationship between lipoprotein(a) and the risk of IHD.
Key words: lipoprotein (a), coronary artery disease, IHD
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