Case Report
Year: 2019 | Month: August | Volume: 6 | Issue: 8 | Pages: 58-62
Renal Epithelioid Variant of Angiomyolipoma – A Rare Case Report
Jyotsna Sahai1, Rakesh Demde2, Reeta Dhar3, Shilpi Sahu3, Asmita Desai1
1Resident, 2Assistant Professor, 3Professor, MGM Medical College, Kamothe, Navi Mumbai.
Corresponding Author: Jyotsna Sahai
ABSTRACT
Epithelioid Angiomyolipoma (EAML) is a rare mesenchymal tumour with malignant potential. The epithelioid variant of angiomyolipoma was first described in 1995 by Martignoni et al as a distinct clinicopathologic variant of AML which is mainly characterized by a predominance of epithelioid cells. Histologically, EAML is characterized by sheets or nests of large polygonal epithelioid cells with abundant eosinophilic or occasionally clear cytoplasm, often with prominent nucleoli, including multinucleated and markedly pleomorphic forms. These tumours share a distinctive perivascular epithelioid cell phenotype, they belong to the PEComa tumour family. Nearly all EAMLs show immunoreactivity for both melanocytic and myoid markers. EAML can pose significant diagnostic challenge on H and E microscopy as it morphologically mimics a variety of neoplasms. An EAML diagnosed by the authors in an adult male patient is presented here.
Key words: Angiomyolipoma, Epithelioid.
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