Review Article
Year: 2020 | Month: October | Volume: 7 | Issue: 10 | Pages: 462-471
Superdisintegrants and Their Inevitable Role in Orodispersible Tablet
Reshma K J1, Senthila S2
1M Pharm, Department of Pharmaceutics, The Dale View College of Pharmacy And Research Centre, Punalal, Thiruvananthapuram, Kerala.
2Associate Professor, Department of Pharmaceutics, The Dale View College of Pharmacy And Research Centre, Punalal, Thiruvananthapuram, Kerala.
Corresponding Author: Reshma K J
ABSTRACT
Oral drug delivery systems provide wide varieties of advantages in recent and current periods. And it is a widely acceptable route by all type of patients. Orodispersible tablets are those solid dosage forms which contain drugs that disintegrate completely in the oral cavity within one minute. In the pharmaceutical industries also they are widely using. The orodispersible tablets get rapidly disintegrate in the oral cavity, they don’t need any requirement of chewing and water. The major component present in the orodispersible tablets are the superdisintegrants. The superdisintegrants are those agents which help to improve the disintegration of the tablet. There are multiple categories of superdisintegrants used in the fast disintegrating or oral disintegrating tablets. They are of synthetic, semi-synthetic, natural, co-processed blends, multifunctional superdisintegrants, etc. This review highlights the different types of superdisintegrants, their mechanism, their properties and ideal characters.
Keywords: Superdisintegrants, Disintegrants, Natural & Synthetic, Co-processed
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