Research Paper
Year: 2020 | Month: November | Volume: 7 | Issue: 11 | Pages: 304-313
The Effect of Giving Edible Amaranth Extract (Amaranthus tricolor) and Moringa Leaves (Moringa oleifera) Extract on Experimental Pregnant Mice towards Hemoglobin Level
Ayu Jani Puspitasari1, Efrida, SpPK (K), M. Kes2, Gusti Revila, M. Kes3
1Postgraduate Student, Midwifery Science Department, Medical Faculty, Andalas University, Padang, Indonesia
2Lecturer, Medical Faculty, Andalas University, Padang, Indonesia
3Lecturer, Medical Faculty, Andalas University, Padang, Indonesia
Corresponding Author: Ayu Jani Puspitasari
ABSTRACT
Pregnant woman needs adequate nutrition to maintain maternal health, fetal development, and preparation for lactation. Inadequate nutrition is one of the causes of anemia in pregnant woman. Anemia in pregnant women in Indonesia is mainly caused by iron deficiency. Pregnant woman with anemia can be at risk of giving birth to low birth weight (LBW). One of the forms of fortification for iron needs can be done by consuming green vegetable including edible amaranth (Amaranthus tricolor) and moringa leaves (Moringa Oleifera). This study aimed to determine the effect of giving edible amaranth and moringa leaves extract in experimental pregnant mice on hemoglobin level and birth weight.
This was an experimental research with posttest only control group design on 15 pregnant mice divided into 3 groups (group 1: control, group 2: treatment with edible amaranth extract, group 3: treatment with moringa leaves extract at a dose of 396 mg/200 g of body weight for 17 days. The research was carried out in the Natural Material Chemistry Laboratory of the Faculty of Pharmaceutical, the animal house of the Biomedical Laboratory and the Biochemistry Laboratory of the Faculty of Medicine, University of Andalas. Statistical test with one way ANOVA, the significance is determined if p<0,05.
The results showed that the mean of hemoglobin level (g/dL) in the control group: 8,98±0,41, treatment 1: 11,57±0,42, and treatment 2: 12,14±0,43. The mean of birth weight (g) in the control group: 2,99±0,04, treatment 1: 3,09±0,32, and treatment 2: 2,91±0,65. There was an effect of giving edible amaranth and moringa leaves extract in experimental pregnant mice on hemoglobin level with a value of p=0,00 (p<0,05) and there was no effect on birth weight (p=0,794).
The conclusion of this study is that there is an effect of giving edible amaranth and moringa leaves extract on hemoglobin level and there is no effect of edible amaranth extract and moringa leaves on birth weight.
Keywords: Anemia, Edible Amaranth Extract, Moringa Leaves Extract, Pregnant Mice.
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