Original Research Article
Year: 2020 | Month: February | Volume: 7 | Issue: 2 | Pages: 315-319
Diagnostic Significance of Platelet Indices in Dengue Fever in Endemic Area
Vijay Kumar Meena1, Shyam Bihari2, S.R Meena3
1PG Resident, 2Assistant Professor, 3Senior Professor and Head,
Department of Medicine, Government Medical College Kota.
Corresponding Author: Vijay Kumar Meena
ABSTRACT
Aim and Objective: Dengue fever is one of the most common arboviral mediated outbreaks reported with increased prevalence year after year with considerable morbidity and mortality. The aim to study role of various platelet indices (MPV, PDW, PCT) in early diagnosis of Dengue fever in patient belong from endemic area, patients admitted in MBS Hospital KOTA, a tertiary care hospital in Rajasthan with a diagnosis of Dengue fever according to WHO protocol from December 2018 to January 2020
Methods: Prospective observational study was undertaken among adult patients in a MBS hospital Kota. 132 patients were studied and analysed. These 132 patients were grouped into three according to the platelet count (<20000,20000- 100000, >100000). The patients admitted in our hospital with features suggestive of Dengue fever were taken for the study and diagnosis was confirmed with Dengue IgM ELISA test. CBC were determined using automated counter, five-part haematology analyser in central laboratory of MBS hospital Kota.
Result; among 132 patients 22Patients had platelet counts below 20,000 the mean PDW was 17.29fl, 80 cases with platelet counts between 20,000 to 100000, the mean PDW was 16.5fl and 30 cases with platelet counts above 100000 the mean PDW was 13.8fl which showed statistically significant difference between the groups (p value 0.001).
The mean MPV values were 9.2fl in 22 patients with platelet counts below 20,000 and 12fl in 80 cases with platelet counts 20,000 to 100000 and 13.7fL in 30 patients with platelet count above 100000. There was statistically significant difference between the groups (p value 0.001).
The mean PCT value were 0.03% in 22 patients with platelet counts below 20,000 and 0.1% in 80 cases with platelet counts 20,000 to 100000 and 0.1% in 30 patients with platelet count above 100000. There was statistically significant difference between the groups (p value 0.001).
Conclusions: Platelet indices are useful parameters in dengue infection. Other than platelet count, PDW, MPV, plateletcrit are useful to monitor dengue fever. Decrease MPV,PCT and increase PDW is significant in platelet count <100000/mm3 and Platelet indices plays significant role in early predictive diagnosis and severity of dengue in endemic area.
Keywords: Dengue, Platelet, fever, PCT, PDW, MPV
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