Review Article
Year: 2020 | Month: February | Volume: 7 | Issue: 2 | Pages: 402-406
Methods of Detecting Cell Proliferation
Sayeeda Sadaf Hashmath1, Hari Aparna Laxmi Gayatri1, Pyata Vamshikrishna1, Charu Suri2, Shravan Kumar3
1Post Graduate Student, 2Professor, 3Reader,
Department of Oral and Maxillofacial Pathology, Sri Sai College of Dental Surgery, Vikarabad
Corresponding Author: Sayeeda Sadaf Hashmath
ABSTRACT
A cell is the structural and functional unit of life. Every cell has to undergo a series of events, called the cell cycle, in order to proliferate and become a part of the cell population and to be functional. There are various mechanisms in our body which distinguish between healthy and diseased cells. Over the years, many methods have been have evolved in order to determine the cell proliferation. Some of them are tedious yet reliable and cost effective while others are advanced and highly accurate but expensive. Though Hematoxylin and Eosin staining method is considered to be gold standard in interpreting the pathology of the lesion, evolution of various methods for detecting cell proliferation, starting from counting the nuecleolar organising regions to determining the number of proliferating cells by imaging method using label free photonic crystal biosensors, have made the work more easier. In this review, different methods of determining cell proliferation have been explained.
Keywords: Cell cycle, Cell division, Cell proliferation
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