Review Paper
Year: 2020 | Month: March | Volume: 7 | Issue: 3 | Pages: 392-396
Review on Locked-in Syndrome
Nolin Johncy1, A. R. Shabaraya2
1Pharm D, 2Principal and Director,
Srinivas College of Pharmacy, Mangalore, India
Corresponding Author: Nolin Johncy
ABSTRACT
The expression "Locked in Syndrome" was established by Plum and Posner in 1966 which adverts to a neurological condition identified with ventral pons infarction. The disorder is symbolized by quadriplegia, inferior paralysis of the cranial nerve and aphonic sustaining only the upward look and motion of eyelid. Patients with locked in syndrome is unerringly sealed within the human form, conscious of their surroundings but with a confined capacity to communicate with it. Cerebrovascular malady is the most driving etiology of LIS. Infarction of the ventral pontine following hindrance of basilar arteries is usually the result. Another significant and recurrent instigation of LIS is brain injury due to trauma. Conveying of messages for LIS persons involves using alternative broadcasting, such as eye blinks or eye movements for a yes-no code or communication boards with alphabets or marks suggested by eye gestures. The initial treatment is on the preservation of an airway and adequate oxygenation. Insurers can be helped to prepare for the expense of treating these seriously impaired patients in the long term by a greater understanding of the outcome for LIS patients. Progressed study is desired to effectively elucidate the advantages of low-level patients in-patient rehabilitation and health care providers need to identify the value of factual diagnosis for the treatment of development plans, giving preference to a team approach that has the ability to manage patients with poor response.
Keywords: Locked in syndrome, quadriplegia, infarction, oxygenation
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