IJRR

International Journal of Research and Review

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Original Research Article

Year: 2020 | Month: June | Volume: 7 | Issue: 6 | Pages: 471-475

Effect of Cyclopentolate Hydrochloride 1% on the Corneal Curvature of Different Refractive Status

Megwas, A.U., Ogbuagu, F.U., Azuamah, Y.C., Nwakamma, G.I., Nwawume, I.C., Ugwoke, G.I.

Department of Optometry, Federal University of Technology, Owerri, Nigeria

Corresponding Author: Megwas, A.U

ABSTRACT

The most significant refractive structure of the eye is the cornea, contributing about two-third of the eye refractive power. This study was carried out to determine the effect of 1% cyclopentolate hydrochloride on the corneal curvature of myopes, hyperopes and emmetropes. Retinoscopy and Subjective refraction were performed on the subjects who satisfied the inclusion criteria to determine their refractive status. The subjects were grouped into three groups of different refractive status: emmetropes, myopes and hyperopes. The corneal anterior curvature was measured monocularly using the Javal-Schiotz keratometer. One drop of 1% cyclopentolate hydrochloride was instilled on the subjects’ eye twice in 10 minutes interval and the anterior corneal curvature reading was repeated after 30, 60 and 90 minutes of instillation from the last drop. A total 124 subjects between 18 and 30 years were used for this study. Forty-two were emmetropes, 54 were myopes and 28 were hyperopes. Results showed that the mean radius of curvature among emmetropes was 8.22 before instillation, and became 8.22, 8.25 and 8.26 after 30, 60 and 90 minutes respectively. The mean corneal radius of curvature measurements among myopes was 7.90 before instillation, and became 7.91, 7.92 and 7.90 after 30, 60 and 90 minutes respectively. The mean corneal radius of curvature measurements before and after instillation of 1% cyclopentolate hydrochloride among hyperopes was 8.38 before instillation, and became 8.40, 8.40 and 8.38 after 30, 60 and 90 minutes respectively. The changes in the mean corneal curvature values were not statistically significant (P>0.05) among the emmetropes, myopes and hyperopes. Further research on age variationswith topical cycloplegics on corneal biometrics were recommended.

Keywords: Emmetropes, Hyperopes, Myopes, Cornea Curvature, Cyclopentolate hydrochloride

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