Case Report
Year: 2021 | Month: February | Volume: 8 | Issue: 2 | Pages: 218-221
DOI: https://doi.org/10.52403/ijrr.20210232
A Case Report on Prednisolone Induced Facial Puffiness and Weight Gain
Erramalla Kiranmai1, Poli Tejaswini2, Chenchu Srividya3, Anchala Sreha Priyusha4, Dudekula Manohar5, Padigala Krishna Kishore6
1-6 Department of Pharmacy Practice [Pharm-D] Intern, P. Rami Reddy Memorial College of Pharmacy, 1-35/1, Prakruthi Nagar, Kadapa-516003, A.P
Corresponding Author: Erramalla Kiranmai
ABSTRACT
Prednisolone is a commonly used catabolic steroid that binds to cytoplasmic receptors and inhibits DNA synthesis. Prednisolone is used as an anti-inflammatory; majorly it causes Cushing Syndrome, edema, muscle weakness, and weight gain. A 6years pediatric female patient was consulted in the pediatric department with chief complaints of swelling in the cheek and weight gain for 1 month. Past medical history includes, she was taking treatment for nephrotic syndrome, which includes Tab. prednisolone 5 mg, 30 mg/day 3-0-3 BD. After 15 days patient had complaints of the swelling of the cheeks and after 4 weeks she had complaints of weight gain [15 kg - 19 kg] on the administration of Tab. Prednisolone is the reason for the hospital admission. Better vigilance is necessary for a safe and effective treatment for each patient. In-order to prevent serious ADR of this drug, close monitoring during the treatment course, and careful management of all patients who receive this medication because corticosteroids cause toxic effects like fluid retention, muscle weakness, etc. If close monitoring is not provided during the treatment course, it can cause permanent disability, morbidity, mortality.
Keywords: Prednisolone, Facial puffiness, adverse drug reaction, Weight gain.
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