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Review Article

Year: 2021 | Month: March | Volume: 8 | Issue: 3 | Pages: 175-181

Drug Related Problems in Chronic Kidney Disease: A Brief Review

Abhishek Pradhan¹, Ambika V², A R Shabaraya³, Chinju Jose¹, Niveditha TV¹, Shwetha N¹

¹Asst. Professor, Department of Pharmacy Practice, Srinivas College of Pharmacy, Mangalore, Karnataka, India – 574143.
²Student, Department of Pharmacy Practice, Srinivas College of Pharmacy, Mangalore, Karnataka, India – 574143.
³Professor & Head, Department of Pharmacy Practice, Srinivas College of Pharmacy, Mangalore, Karnataka, India – 574143

Corresponding Author: Ambika V

ABSTRACT

Drug Related Problems (DRPs), also known as Medication Related Problems or MRPs, are the events which occur due to the drugs used for treatment, which actually or potentially interfere with the desired therapeutic outcome. Actual DRPs are those which are actually observed in the patient whereas potential DRPs are those which may develop if appropriate interventions are not met. Chronic Kidney Disease (CKD) can be defined as abnormalities in the kidney structure or function which is present for at least 3 months and has some impact on the health of the individual affected. CKD patients are said to be at high risk for DRPs due to polypharmacy and moreover, due to their impaired renal excretion. In these patients, DRPs can cause decreased quality of life, increased length of hospital stay, increased health-care cost, and may even increase the risk of morbidity and mortality.
It is considered that the necessity of dose adjustment or drug avoidance in patients with kidney disease is probably under-estimated in clinical practice. This article focuses on the review of published articles on drug related problems in patients with chronic kidney disease. The aim of this review is to improve the understanding regarding the prevalence, risk factors, identification, classification, etiology and the role of pharmacist in the management of DRPs in CKD patients.

Keywords: Drug Related Problems, Chronic Kidney Disease, Pharmaceutical Care.

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