Review Article
Year: 2021 | Month: March | Volume: 8 | Issue: 3 | Pages: 403-409
Risk Factors for Developing Drug Related Problems in Patients with Cardiovascular Diseases
Shwetha N1, Abhishek Pradhan2, A. R. Shabaraya3, Niveditha T V4, Chinju Jose5, Ambika V6
1-6 Department of Pharmacy Practice, Srinivas College of Pharmacy, Valachil, Mangalore
Corresponding Author: Shwetha N
ABSTRACT
Medicines have been playing important role in the cure, palliation as well as inhibition of diseases, but they also expose patients to Drug related problems (DRPs). Drug related problems constituted a major safety issue among patients with cardiovascular diseases (CVDs). These not only cause patient harm and increase health care costs but also lead to negative clinical outcomes1. Prescriptions containing multiple medications not only increase complexity of treatment regimen but also make the patient poorly adherent to those prescribed medications 2. According to a study, the frequency of Drug Related Problems (DRPs) has been reported to be as high as 69% and 78% respectively in patients with cardiovascular diseases1,3. The aim of the study is to assess the risk factors for developing drug related problems in patients with cardiovascular diseases. Analysis of original research articles has been done to assess the risk factors associated with DRPs in patients with cardiovascular diseases. The common DRPs were found to be inappropriate selection of drugs, improper dosages, adverse drug reactions and drug interactions4,5. The risk factors found to be associated with DRPs in patients with CVDs were old age, female gender, poly pharmacy, and potential drug-drug interactions, multiple diseases, lack of therapeutic monitoring, need of additional drug therapy, associated co-morbidities, length of hospital stay and drugs like anti coagulants, diuretics, beta blockers and lipid lowering agents etc6,7. Hence there is a need for clinical pharmacist’s interventions to identify, monitor and prevent the risk of developing Drug Related Problems and contribute to improve the clinical outcome in patients with cardiovascular diseases.
Keywords: Drug related problems, cardiovascular diseases, risk factors and clinical outcome.
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