Original Research Article
Year: 2021 | Month: March | Volume: 8 | Issue: 3 | Pages: 631-636
Correlation of 24-Hour Urinary Protein Excretion and Spot Urine Protein-Creatinine Ratio in Women with Preeclampsia: A Cross Sectional Study
K. Hima Bindu1, S. Krishnmurty2, Amol Kamble3
1Associate Professor, Department of OBG, CAIMS Karimnagar.
2Associate Professor, 3M.Ch. Post Graduate, Department of Urology, CAIMS Karimnagar.
Corresponding Author: S. Krishnmurthy
ABSTRACT
Objective: To examine the correlation between spot urine PCR and 24-hour urine protein excretion in patients being evaluated for preeclampsia.
Material and Methods: A cross sectional study was conducted on 100 patients at the Department of Obstetrics and Gynecology at Chalmeda Anand Rao Institute of Medical Sciences, Karimnagar, Telangana State for a period from December 2019 to August 2020, with inclusion of singleton viable pregnancy, Gestational age between 24 and 38 weeks, Confirmed by last menstrual period and early ultrasound.
Result: Among 100 patients having mean age of 25 ± 3.266 years, among the patients 19% percent of the patients had past history of preeclampsia. Mean gestational age for the patients was 32.39 ± 3.42 weeks. Study showed 62 % of moderate urinary protein levels. There was significant correlation between spot PCR and 24 hour urine protein collection (spearman’s rho=0.7, P<0.0001).
Conclusion: Urine protein: creatine ratio is one of the important investigation in hypertensive disorder of the pregnancy. Spot Urine protein: creatine ratio can reliably be taken as a simple, accurate, and convenient replacement for tedious, time consuming 24 hour urine protein estimation, especially in countries like India where hospitals are flooded with a large number of in-patients. Therefore Urine protein: creatine ratio estimation should be introduced and adopted in practice in testing for proteinuria.
Keywords: Preeclampsia, protein: creatine ratio, Dipstick, Proteinuria.
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