Original Research Article
Year: 2021 | Month: July | Volume: 8 | Issue: 7 | Pages: 207-211
DOI: https://doi.org/10.52403/ijrr.20210728
Study Comparing the Liver Enzymes in Hypertensive and Normotensive Patients with Type 2 Diabetes
Rishad Ahmed
Associate Professor, Dept. of Medicine, KPC Medical College and Hospital, Kolkata, West Bengal, India
ABSTRACT
Objective: There were few clinical trials which indicate altered liver biochemical findings in diabetic patients, but through investigation to compare the liver enzymes in-between hypertensive and normotensive patients with type 2 diabetes was not evaluated. Thus main objective of current study was to compare the liver enzymes in hypertensive and normotensive patients with type 2 diabetes.
Materials and Methods: This was a retrospective observational study conducted in a tertiary medical teaching hospital in Kolkata. Hospital OPD reports and patients clinical case records were used to fetch the required data in a predesigned clinical record pro forma.
Result: Total 180 patients were participated in this observational retrospective trial where 33% patient were normotensive but having T2DM and 67% patients were hypertensive with T2DM. There were no statistically significant differences between the study variables among both the groups. However elevated level of GGT, ALT and AST were observed in T2DM normotensive patients as compare to T2DM hypertensive patients. abnormal liver functions were recorded in patients with uncontrolled diabetes as compared to patients with good control (p<0.05).
Conclusion: The current study concluded that elevated liver enzymes like bilirubin, GGT, SGOT and SGPT were common among diabetes mellitus patients and comparable with patients with hypertensive as well as normotensive patients with diabetes mellitus.
Keywords: Liver enzymes, T2DM, hypertension.
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