Original Research Article
Year: 2021 | Month: August | Volume: 8 | Issue: 8 | Pages: 27-30
DOI: https://doi.org/10.52403/ijrr.20210806
Comparison of Red Cell Distribution Width (RDW) Value in Congestive Heart Failure (CHF) Patients with Normal Persons
Marhani Yunita1, Herman Hariman2
1,2Department of Clinical Pathology, Faculty of Medicine of University of Sumatera Utara / General Hospital Haji Adam Malik Medan, Indonesia.
Corresponding Author: Marhani Yunita
ABSTRACT
Congestive Heart Failure (CHF) is a complex clinical symptom that is often characterized by structural abnormalities or cardiac dysfunction that impairs the ability of the left ventricle (LV) to fill or pump blood, especially during physical activity. Red Cell Distribution Width (RDW) is a simple, fast, inexpensive and direct hematological parameter, which reflects the level of anisocytosis in vivo. The association between impaired hematopoiesis and cardiac dysfunction is based on the fact that many different conditions are associated with increased heterogeneity of erythrocyte volume, which can be concurrently present in patients with heart failure, while anisocytosis can also directly contribute to the development and worsening of heart failure. This study aims to provide a comparison of RDW values between CHF patients and normal people. This study uses a case control study design where as many as 20 people with CHF will be compared their RDW values with 20 normal people. From a total of 40 patients, the average RDW value in CHF patients was 17.7±2.4 higher than the average RDW value for normal people was 12.6±0.4 and from the results of statistical analysis using the Independent Student t test obtained p value <0.001. There is a significant difference between the RDW values of CHF patients compared to normal people.
Keywords: Congestive Heart Failure, CHF, Red Cell Distribution Width, RDW.
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