Case Report
Year: 2021 | Month: September | Volume: 8 | Issue: 9 | Pages: 149-153
DOI: https://doi.org/10.52403/ijrr.20210921
Cytomegalovirus Encephalitis with Decreased Vision in Immunocompromised Patients Treated with Valganciclovir: Case Report
Erwin Hardiansyah1, Paulus Sugianto2
1Neurology Resident of Faculty of Medicine Airlangga University/Dr. Soetomo General Hospital Surabaya
2Staff of Department Neurology Faculty of Medicine Airlangga University/Dr. Soetomo General Hospital Surabaya
Corresponding Author: Erwin Hardiansyah
ABSTRACT
Introduction: Cytomegalovirus (CMV) is a significant cause of morbidity and mortality in patients with Acquired Immune Deficiency Syndrome (AIDS). Almost all Human Immunodeficiency Virus (HIV) infected patients develop CMV rapidly with manifestation in the central nervous system. Most CMV encephalitis is preceded by the presence of CMV in other places. Therefore, immediate therapy will be more effective and the delay in therapy can be detrimental.
Case: A 40-year-old man with the major complaint of vision decrease in both eyes for 3 months claimed that he felt worse after 7 days, accompanied by headache and fever. This patient was diagnosed with HIV 2 years ago. The examination obtained GCS 456, negative meningeal sign, headache with NRS 7. The visual acuity of the right eye was negative light perception and in the left eye of vision 1/300. The patient experienced clinical improvement after oral Valganciclovir therapy with a dose of 2x450 mg.
Conclusion: CMV encephalitis must be considered to diagnose earlier in HIV patients with complaints of decreased vision. With valganciclovir 2x450 mg tablets improve reduction of headache scale NRS from 7 to 2, increasing left eye vision from 1/300 to 6/60.
Keywords: Encephalitis CMV, HIV, Valganciclovir.
[PDF Full Text]