Review Paper
Year: 2022 | Month: December | Volume: 9 | Issue: 12 | Pages: 334-341
DOI: https://doi.org/10.52403/ijrr.20221237
Chemistry and Pharmacological Exploration of Benzoxazole Derivatives
Akhila. S1, Hima. C. S2, Dr. Shaiju S Dharan3
1PG Student, Ezhuthachan College of Pharmaceutical Sciences, Marayamuttom, Neyyattinkara, Kerala 695124, India
2Associate professor, Ezhuthachan College of Pharmaceutical Sciences, Marayamuttom, Neyyantinkara, Kerala 695124, India
3Principal, Ezhuthachan College of Pharmaceutical Sciences, Marayamuttom, Neyyanttinkara, Kerala 695124, India
Corresponding Author: Akhila. S
GRAPHICAL ABSTRACT
Benzene attached with oxazole moiety constitutes extensive range of pharmacological activity. Numerous pharmacological actions including anticancer, analgesic, anti-inflammatory, antihyperglycemic, antimicrobial, antitubercular, anticonvulsant have been associated with benzoxazole scaffold.
ABSTRACT
Benzoxazole is one of the most prominent heterocyclic structures and is found in an extensive range of biologically active compounds. It is one of the often occurring heterocyclic nitrogen-containing moieties that perform as the primary active elements of pharmaceutical compounds. It can be viewed as isosteres of the naturally occurring guanine and adenine nucleic bases since they interact effectively with the polymeric components of biological systems. A wide range of biological features, including analgesic, antibacterial, anti-inflammatory, anti-hyperglycemic, anticancer, antiviral, antifungal, antileishmanial, and antitubercular activities, they are significantly influenced by heterocyclic compounds with a benzoxazole nucleus.
Keywords: Benzoxazole, anticancer, antihyperglycemic, antibacterial, Caboxamycin, Pseudopteroxazole
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