Case Report
Year: 2022 | Month: September | Volume: 9 | Issue: 9 | Pages: 188-193
DOI: https://doi.org/10.52403/ijrr.20220919
Autoimmune Encephalitis Following COVID-19 Infection with Brain Magnetic Resonance Imaging Mimicking Metachromatic Leukodystrophy in an Adolescent: A Case Report
Mohd Luthfi B1, Rahmi Lestari2, Iskandar Syarif2
1Department of Paediatric, Faculty of Medicine, Universitas Andalas, Indonesia
2Neurologic Subdivision, Department of Paediatric, Faculty of Medicine, Universitas Andalas, Indonesia
Corresponding Author: Mohd Luthfi B
ABSTRACT
Neurological manifestations such as encephalitis, ataxia, headache, seizure, papilledema, and ophthalmoplegia have been reported in several pediatric Coronavirus Disease 2019 (COVID-19) studies. There are multiple pathogeneses that may underlie the clinical manifestations. Herein, we reported a case of adolescent with clinical manifestation like encephalitis with positive Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV-2) antibody, and suspected Metachromatic Leukodystrophy (MLD) in brain Magnetic Resonance Imaging (MRI) finding. The patient did not respond to corticosteroid therapy but showed clinical improvement over intravenous immunoglobulin (IVIG) therapy. The possibility of COVID-19 infection in neurological disorders should be considered in pediatric patients.
Keywords: encephalitis, COVID-19, adolescent, IVIG
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